Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

Validation of the compound effects in GFP-tagged clonal cell lines and wild-type cells. (A) Effects of treatment with 100 nM dBET6 for 3 h in newly generated GFP-tagged clonal cell lines. (B) Effects of treatment with 100 nM dBET6 for 3 h in HAP1 wild-type cells shown by immunofluorescence staining. (C) Western blot of wild-type HAP1 cells and GFP-tagged clonal cell lines.

This Article

  1. Published in Advance November 17, 2020, doi: 10.1101/gr.261503.120 Genome Res. 30: 1846-1855

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research