The performance of Anchor type Predictor. (A) F1-score of ATP evaluated using four standard classifiers across four HiChIP data sets. (B) ROC curves of ATP in K562-YY1 HiChIP data (Supplemental Methods). (C) The F1-score performance of ATP in four HiChIP data sets with increasing number of top-ranked features by fivefold cross-validation. The vertical line indicates point at which ATP achieved close to optimal performance with a modest input of 12 features. (D) Pearson's correlation combined with hierarchical clustering for K562 cell features. The colored bars on the right side indicate the identity of each hierarchical cluster. Colored bars at the bottom mark the feature correlation coefficient, R. (E) Heat map displaying YY1 and ELF1 ChIP-seq signals across YY1 peaks (n = 3142). (F) Comparison of YY1 and ELF1 ChIP-seq peaks signals by distance from YY1 peak summit. (G) Feature importance for the top 12 features in K562-YY1 HiChIP data set with fivefold cross-validation. Error bars indicate the standard deviation.
