Distinctive regulatory architectures of germline-active and somatic genes in C. elegans

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Figure 5.
Figure 5.

Ten-base-pair WW periodicity at ubiquitous promoters is a feature of nonmammalian genomes. (A) Nucleosome occupancy probability scores (red; left axis) and 10-bp WW periodicity (blue; right axis) at worm, fly, zebrafish, mouse, and human TSSs. (B) Normalized distribution of pairwise distances between WW dinucleotides found in the sequences from −50 bp to +300 bp relative to TSSs, for genes with broad expression (top row; 20% lowest gene expression CV scores) or regulated expression (bottom row; 20% highest gene expression CV scores) in worm, fly, zebrafish, mice, and human. (C) Associated WW power spectral density values at a 10-bp period.

This Article

  1. Genome Res. 30: 1752-1765

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