Generalized linear regression (GLM) analysis of differential gene expression between collared flycatcher and pied flycatcher against the number of protein–protein interactions (PPIs), tissue specificity (τ), intra-species variation in gene expression (ϕ), the ratio of nonsynonymous to synonymous diversity (πN/πS) and divergence (dN/dS), and genomic differentiation between collared flycatcher and pied flycatcher (FST) as candidate explanatory variables separately for five different tissues
| Brain | Heart | Kidney | Liver | Testis | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| t-stat | P-value | t-stat | P-value | t-stat | P-value | t-stat | P-value | t-stat | P-value | |
| PPI | 0.33 | 7.38 × 10−1 | −1.81 | 7.03 × 10−2 | −0.50 | 9.60 × 10−1 | −1.64 | 1.00 × 10−1 | −0.52 | 6.04 × 10−1 |
| τ | 0.90 | 3.67 × 10−1 | 2.26 | 2.37 × 10−2 | 4.25 | 2.11 × 10−5 | 3.22 | 1.26 × 10−3 | 5.62 | 1.88 × 10−8 |
| ϕ | −1.59 | 1.13 × 10−1 | −1.87 | 6.21 × 10−2 | −3.60 | 3.23 × 10−4 | −3.19 | 1.43 × 10−3 | −4.36 | 1.33 × 10−5 |
| πN/πS | −0.12 | 9.03 × 10−1 | 0.84 | 3.98 × 10−1 | −0.28 | 7.82 × 10−1 | 0.23 | 8.20 × 10−1 | 0.62 | 5.38 × 10−1 |
| dN/dS | 3.20 | 1.39 × 10−3 | 1.67 | 9.41 × 10−2 | −0.52 | 6.04 × 10−1 | 2.36 | 1.82 × 10−2 | 1.66 | 9.66 × 10−2 |
| FST | 0.34 | 7.35 × 10−1 | 1.05 | 2.95 × 10−1 | 3.48 | 5.02 × 10−4 | 3.15 | 1.64 × 10−3 | 4.79 | 1.69 × 10−6 |
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For each tissue, the t-statistic of the association and P-values are reported. Significant associations (P-value < 0.05) are highlighted in bold and underlined if significance was retained after Holm-Bonferroni correction.
