Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells

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Figure 3.
Figure 3.

Copy number changes at week 4. (A) Hamster genome, growth at week 4 compared to week 0; 0 nM paclitaxel. (B) Human genome, growth at week 4 compared to week 0; 0 nM paclitaxel. (C) Hamster genome, 75 nM paclitaxel compared to 0 nM paclitaxel; week 4. (D) Human genome, 75 nM paclitaxel compared to 0 nM paclitaxel; week 4. Changes on log2 scale averaged across the six RH pools.

This Article

  1. Published in Advance September 2, 2020, doi: 10.1101/gr.262204.120 Genome Res. 30: 1458-1467

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