HDA6-dependent histone deacetylation regulates mRNA polyadenylation in Arabidopsis

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Figure 1.
Figure 1.

Mutation of HDA6 affects mRNA polyadenylation. (A) Fraction of genes with different number of poly(A) sites. (B) Venn diagram of identified APA genes by different threshold values. A total of 10,681 genes with at least two poly(A) sites were used for selections. PSU indicates the frequency of poly(A) site usage. (C) Folded cumulative distribution frequency (CDF) of PSUs of Col-0 and hda6. Only poly(A) sites with padj < 0.05 were selected for plotting. Three replicates were plotted separately. The y-axis indicates the fraction of poly(A) sites. (D) Heat map of PSUs of Col-0 and hda6. Only poly(A) sites with padj < 0.05 were selected for plotting. The scale bar is on the bottom.

This Article

  1. Published in Advance August 5, 2020, doi: 10.1101/gr.255232.119 Genome Res. 30: 1407-1417

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