Sex-specific genetic regulation is associated with adipocyte differentiation. Adipogenesis time course gene expression data are shown for human cultured SGBS cells, human adipose-derived stromal cells (ASCs), and murine 3T3-L1 cells. For each time course profile, we performed a likelihood ratio test (LRT) to evaluate whether the gene in question changes dynamically during differentiation. The false discovery rates (fdrs) correspond to the LRTs. We also show the expression percentiles (%tile) for each gene, considering all expressed genes at the time point of terminal differentiation, thereby representing the relative degree of expression in mature adipocytes. All genes indicated show evidence for dynamic expression during human adipogenesis and a substantial degree of expression in human adipocytes. Smooth curves were generated using Loess regression, and associated 95% confidence intervals are shown in dark gray.
