Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis

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Figure 6.
Figure 6.

Sex-specific genetic regulation is associated with sex-biased gene expression. Six cases illustrate sex-specific eQTLs (P < 1 × 10−4) that overlap with differentially expressed genes (FDR <0.05). Note the congruence between the sex-specificities of gene expression and the corresponding sex-specificities of allelic effects. The results suggest that differential expression could be partially accounted for by differential genetic regulation at sex-specific eQTLs.

This Article

  1. Published in Advance September 23, 2020, doi: 10.1101/gr.264614.120 Genome Res. 30: 1379-1392

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