Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

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Figure 4.
Figure 4.

Phenotypic comparison between klf3 mutants and morphants. (A) WISH showing the expression of hbbe2 (also known as βe2-globin) in klf3 WT, morphants, and mutants. The black arrowheads indicate hbbe2 expression in erythroid lineages. (B) Quantitative real-time PCR showing the expression of Klf members klf1, klf3, klf4b, klf6a, and klf8 in klf3 mutants.

This Article

  1. Genome Res. 30: 118-126

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