The 22q11 low copy repeats are characterized by unprecedented size and structural variability

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Fiber FISH-mapped haplotypes of LCR22A and LCR22D observed in a cohort of 33 cell lines. (A) Twenty-six haplotypes observed for LCR22A. Haplotypes are aligned at the distal unique anchor of LCR22A. (B) Proximal and distal haplotypes observed for LCR22D. Filled, colored arrows represent copies of duplicons, and hatched arrows represent partial copies of duplicons of the same color. Size estimates of individual SD22s are shown (upper left). Frequencies of haplotypes are depicted on the right (i.e., x9, x1, etc.).

This Article

  1. Genome Res. 29: 1389-1401

Preprint Server