Figure 6.
Effect of bubble restoration on the reconstruction of the CALC BGC. Schematic representation of repeat collapsing and consensus deterioration in the case of the CALC BGC assembly. While SPAdes outputs a single (and incorrect) consensus sequence of all three collapsed A-domains, these three sequences are not identical. In contrast, biosyntheticSPAdes utilized restored domains and reconstructed their distinct sequences with 100% accuracy (as compared to 99.6% accuracy for SPAdes). Numbers near dashed vertical lines represent the column numbers in the multiple alignment of three A-domain.
