Figure 9.
Analysis of clock component gene expression in skeletal muscle from Drosophila strains with different lifespans. (A) Analysis of long-lived La flies and parental Ra flies and of (B) DGRP lines with distinct median lifespan indicates that the expression of timeless and of other circadian clock components sometimes correlates with increased lifespan; SEM with n = 3; (*) P < 0.05. This suggests that increased timeless expression in muscle correlates with but is not a strict prerequisite for lifespan extension. Increased vri expression also correlates with lifespan extension in both La and Ra lines (A) and DGRP lines (B).
