Figure 6.
The two main haplotype clusters around Cyp9k1 in Burkina Faso, Ghana, and Guinea are associated with respective CNV alleles. Points are jittered to show overlapping data. Lines show least-squares regression through the data. (A) Strong correlation between Cyp9k1_Dup11 and haplotype Cluster 1. Most of the points lie on a line of slope 0.5, indicating that Cyp9k1_Dup11 is found most frequently as a triplication (two extra copies per chromosome), although both lower and higher copy number versions of this CNV exist. (B) Weaker correlation between Cyp9k1_Dup15 and haplotype Cluster 2.
