Exome-wide assessment of the functional impact and pathogenicity of multinucleotide mutations

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Figure 1.
Figure 1.

Properties of MNVs. (A) Schematic showing how sim-MNVs, two variants that occur simultaneously, are defined as having two variants with identical allele frequencies, and con-MNVs, two variants that occur consecutively, as having different allele frequencies. (B) Proportion of pairs of heterozygous variants (possible MNVs) that phase to the same haplotype as a function of distance separated by sim and con. (C) The number of sim-MNVs and con-MNVs by distance between the two variants.

This Article

  1. Genome Res. 29: 1047-1056

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