methyl-ATAC-seq measures DNA methylation at accessible chromatin

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Figure 2.
Figure 2.

Comparison of methods. (A) Omni-ATAC-seq and mATAC-seq share a majority of peaks. (B) Features at peaks are similar for mATAC-seq and Omni-ATAC-seq. (C,D) Accessibility in mATAC-seq is comparable to Omni-ATAC-seq at gene bodies ±2 kb, n = 21,305. (E,F) Methylation reported by mATAC is comparable to WGBS at gene bodies ±2 kb, n = 21,305, although WGBS includes data absent from mATAC.

This Article

  1. Published in Advance June 3, 2019, doi: 10.1101/gr.245399.118 Genome Res. 29: 969-977

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