
Gene expression similarities compared with regulatory regions. (A) Genes that have their promoter regions shared (in operons and head-to-head) have significantly more related spatiotemporal gene expression as measured by the Euclidean distance of 35-dimensional expression space than do genes oriented head-to-tail, tail-to-tail, or random pairs. (B) Genomic distance of gene pairs. Labels for gene orientation are as follows: (O) operon; (HH) head-to-head; (HT) head-to-tail; (TT) tail-to-tail; (R) random. Arrows indicate transcriptional direction of the genes analyzed.











