Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans

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Figure 4.
Figure 4.

New subtelomere formation in wild isolates. (A) Internal genes were duplicated to Chr VR subtelomere. The figure shows a putative gene model of the Chr VR subtelomere. Upper panel: internal gene model; lower panel: subtelomeric gene model. (B) TALT copy numbers among wild isolates (Supplemental Table S3). (C) Normalized coverage mapped on the duplicated segment of wild isolates with high TALT copy number (red) strains and low TALT copy number (blue) strains. (D) Haplotype blocks on Chr V of seven strains that have high TALT copy numbers. (E) Phylogenic tree of reference N2 and 151 wild strains whose genomes have been fully sequenced. Strains marked with red color contain several copies of TALT.

This Article

  1. Published in Advance May 23, 2019, doi: 10.1101/gr.246082.118 Genome Res. 29: 1023-1035

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