
The MED30 Mediator subunit facilitates Nipped-B association with promoters in BG3 cells. An example of MED30 protein depletion is in Supplemental Figure S3A. (A) Effects of MED30 depletion (iMED30) on Nipped-B localization. (B) Effects of MED30 depletion on SA localization. All changes in Nipped-B and SA occupancy are statistically significant except at the centers of early origins (Supplemental Table S2).











