PepQuery enables fast, accurate, and convenient proteomic validation of novel genomic alterations

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Figure 4.
Figure 4.

Evaluation of the ability of PepQuery to validate novel splice junctions. (A) Novel splice-junction peptide identification result. (B,C) Classification of the novel junction peptides reported by the original study but not by PepQuery (orange sections in the large circles). I: Peptides removed by competitive filtering based on reference sequences. II: Peptides removed by competitive filtering based on unrestricted modification searching. III: Remaining false negatives.

This Article

  1. Genome Res. 29: 485-493

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