
Figure 3.
NPPs of SMG1, RAN, and NME1. HRR genes show coevolution within certain clades: (A) SMG1 coevolved with ATR in protists and fungi; (B) RAN coevolved with CHEK2 in plants and across all 578 eukaryotes; and (C) NME1 highly coevolved with H2AFX in plants and animals.











