Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

RIDLs correlate with differential localization of lncRNA transcripts from the same locus. Distribution of differences between RCI mean of transcripts with nuclear RIDL (mean RCI(A)) and RCI mean of transcripts without nuclear RIDL (mean RCI(B)). A positive value indicates that RIDL-carrying transcripts are more nuclear-enriched than non-RIDL transcripts. Data were calculated individually for every gene that has one or more RIDL-transcript and one or more non-RIDL transcript expressed in a given cell line. Numbers inside the boxplots indicate the number of gene loci analyzed for each cell line. Horizontal bar indicates the median. Here nuclear RIDL refers to L1AP16, MIRb, MIRc, and L2b. P-values obtained from one-sided t-test are shown (in red when P < 0.05).

This Article

  1. Genome Res. 29: 208-222

Preprint Server