RNA-seq as a tool for evaluating human embryo competence

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Figure 4.
Figure 4.

RNA-based karyotype-associated gene sets. (A) Schematic depicting RNA-based karyotype differential expression analysis: 15 aneuploid (by RNA) versus 20 euploid WE samples. (B) Volcano plot of differentially expressed genes from RNA-based karyotype differential expression analysis. Red indicates significant differential expression (BH-adjusted P-value <0.05). (C) Gene Ontology (GO) enriched terms for genes up-regulated in the aneuploid samples: (left) cellular compartment; (right) biological process. (D) Boxplots of selected differentially expressed genes from the RNA-based karyotype differential expression analysis (BH-adjusted P-value <0.05). Aneuploid samples are in red; euploid samples, in gray.

This Article

  1. Genome Res. 29: 1705-1718

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