Environmentally induced plasticity of programmed DNA elimination boosts somatic variability in Paramecium tetraurelia

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Figure 2.
Figure 2.

PDE inefficiency shows a U-shaped relationship with temperature. (A–C) Bland-Altman plots displaying the Log2 fold change of IRSs from F0 to F1 for 25°C, 32°C, and 18°C. Statistically significant IRS transitions (binomial test, Padj < 0.05) are shown as filled colored circles: 25°C (dark and light blue circles); 32°C (red and orange circles); 18°C (dark and light green circles) (dark color: IRSF1 > IRSF0; light color: IRSF1 < IRSF0). Position on the x-axis reflects the log-transformed initial (F0) state of the IRSs (x-axis labels are IRSs before log transformation). (D) Counts of statistically significant IRS transitions (Padj < 0.05) after nuclear differentiation at 18°C (green), 25°C (blue), and 32°C (red). The number of somatic IESs experiencing an upward or downward IRS transition is shown above and below the horizontal dashed line, respectively.

This Article

  1. Published in Advance September 23, 2019, doi: 10.1101/gr.245332.118 Genome Res. 29: 1693-1704

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