
Hypomethylation of MHM loci relative to the entire Z Chromosome or repeats on the Z Chromosome in females. In the graphs, DNA methylation of MHM1 and MHM2 is compared with that of the Z Chromosome or repeats on the Z Chromosome for males and females. Coordinates of repetitive sequences were obtained from RepeatMasker track (last update: 2016-04-14) of the UCSC Table Browser. Statistical significance was evaluated using Mann–Whitney U tests. (***) P < 0.001, (NS) not significant.











