Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels

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Figure 3.
Figure 3.

Heritability analysis of AAs and FAs. We estimated broad-sense heritability (H2) of metabolic traits based on a set of 51 RILs that were measured at least three times. The bars indicate the H2, where the dashed line indicates a permutation-based false discovery rate (FDR) of 5% (based on 1000 permutations). We found evidence for strong, significant, heritable variation in most AA (A) and FA (B) abundances, ranging from 0.32 to 0.82 (FDR = 0.05). Only for FA C15:1 and C22:6 no significant H2 was found.

This Article

  1. Genome Res. 28: 1296-1308

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