Cover image
An artistic representation of an R-loop bound by a protein. An R-loop is a three-stranded nucleic acid structure that comprises an RNA/DNA hybrid with a displaced single-stranded DNA. In this issue, Wang et al. identified hundreds of proteins that interact with R-loops in human cells. (Cover artwork by Colleen K. McGarry. [For details, see Wang et al., pp. 1405–1414.])
