A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

TFAM binding and mt-DGF pattern in HeLa cells. (A) An mtDNA map of the DGF sites in HeLa cells (inner histograms), along with the low TFAM (blue bars) and high TFAM sites (red bars). (B) The proportion of high and low TFAM sites among mt-DGF sites in HeLa cells: (y-axis) the group of tested TFAM sites; (x-axis) number of sites. DGF sites are in blue, and non-DGF sites are in orange.

This Article

  1. Published in Advance July 12, 2018, doi: 10.1101/gr.230409.117 Genome Res. 28: 1158-1168

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research