Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1.
Figure 1.

Differences between bacterial and eukaryotic m6dA methylomes and a novel approach for mapping m6dA events in eukaryotic organisms. (A) Comparison between bacterial and eukaryotic m6dA methylomes over three aspects. (B) A novel approach for mapping and characterizing m6dA events in eukaryotic genomes. The novel approach, including a set of methods as summarized on the left, is comprehensively evaluated using subsampled bacterial m6dA methylome data and applied to Chlamydomonas reinhardtii (green algae) and human lymphoblastoid cells (LCLs).

This Article

  1. Genome Res. 28: 1067-1078

Preprint Server