Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations

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Figure 2.
Figure 2.

Expression levels of known pluripotency and lineage-primed markers. (A) Violin and jitter plots and t-SNE plots for expression of top pluripotency markers. Each point represents a single cell. The color gradient in the t-SNE plot represents the relative expression level of the gene in a cell across the whole population and subpopulations: (light gray) low; (dark purple) high. (B) Heatmap of the mean expression of known markers within each subpopulation. The upper panel shows the classifications of genes into pluripotency and lineage-primed markers.

This Article

  1. Genome Res. 28: 1053-1066

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