Comprehensive viral enrichment enables sensitive respiratory virus genomic identification and analysis by next generation sequencing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

Distribution of sequence reads for clinical samples enriched with virus-specific probes. The frequency of reads identified by Kraken for each sample with and without enrichment (H:hybridized; NH: nonhybridized) is shown in bar graphs for each viral family/subfamily tested: (A) Coronavirinae; (B) Adenoviridae; (C) Parvovirinae; (D) Picornaviridae; (E) Paramyxoviridae; (F) Pneumoviridae; (G) Orthomyxoviridae. Viral Ct is shown below the bar graphs. (ND) Ct not available. Abbreviations of virus names are listed in Supplemental Table S1.

This Article

  1. Genome Res. 28: 869-877

Preprint Server