Comprehensive viral enrichment enables sensitive respiratory virus genomic identification and analysis by next generation sequencing

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Figure 1.
Figure 1.

Distribution of sequence reads for reference samples enriched with virus-specific probes. The frequency of reads identified by Kraken for each sample with and without enrichment (H: hybridized; NH: nonhybridized) is shown in bar graphs for each viral family/subfamily tested: (A) Coronavirinae; (B) Adenoviridae; (C) Parvovirinae; (D) Picornaviridae; (E) Paramyxoviridae; (F) Pneumoviridae; (G) Orthomyxoviridae. (*) Frequency of reads obtained from BWA-MEM read mapping. Abbreviations of virus names are listed in Supplemental Table S1.

This Article

  1. Genome Res. 28: 869-877

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