Figure 8.
Traversal of optical mapping fusions using short-read sequencing breakpoint calls. Complex rearrangements of many small genomic fragments result in gaps in the fusion maps, because these fragments are too small to be uniquely aligned to the reference genome. Of the 86 optical mapping gaps traversed (348 kb mean gap length), the length of breakpoint traversals differed by 2024 bp on average. Shown are three examples of fusion gaps >0.5 Mb encompassing 6–9 GRIDSS breakpoints.
