Double insertion of transposable elements provides a substrate for the evolution of satellite DNA

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Figure 1.
Figure 1.

Three mechanisms of tandem TE formation. (A) Ectopic recombination between long-terminal repeats (LTRs; shown in yellow) generates tandem LTR retrotransposons with shared LTRs. (B) Circularization and rolling circle replication of a TE, followed by insertion of the resulting concatemer. The possible mechanism(s) of circularization remains unclear. (C) Two insertions of a TE at the same target site (shown in magenta). Note the preservation of the target site within the tandem junction.

This Article

  1. Published in Advance March 27, 2018, doi: 10.1101/gr.231472.117 Genome Res. 28: 714-725

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