Figure 5.
Rapid evolution of short H2As. (A) Pairwise amino acid identities (y-axis) between pairs of mammalian H2A proteins as a function of species divergence time (x-axis) (see Methods). Marsupial H2A.R proteins 1 and 2 are shown as single points, since each is represented by only two species diverged by 78 million years. (B) Portions of alignments surrounding positively selected sites in simian primate H2A.P genes (PAML, top left box). (C) A portion of the alignment of simian primate H2A.B proteins showing a positively selected codon at site 38 (colored amino acids), identified by FUBAR.
