Figure 5.
Comparison of ZFX and ZNF711 binding at promoters in MCF-7 cells. (A) Scatterplot of the normalized ZFX versus ZNF711 ChIP-seq tags for the union set of ZFX and ZNF711 binding sites found in promoters (ρ = 0.85, Spearman's rank correlation coefficient). (B) Average ZFX (red) and ZNF711 (blue) ChIP-seq signal ±2 kb from the TSS of promoters bound by ZNF711 in MCF-7. (C) Comparison of expressed genes having ZFX or ZNF711 bound at their promoters in MCF-7. (D) Examples of ZFX and ZNF711 binding at CpG island promoters for two genes down-regulated upon knockdown of both ZFX and ZNF711 in MCF-7.
