Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

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Figure 6.
Figure 6.

HMRs gained on parallel lineages are associated with similar transcription factors and developmental genes. (A) Enrichment of transcription factor binding sites in HMR birth and extension regions on the human lineage and mouse lineage. (*) Factors enriched in both lineages. (B) Lineage-specific HMRs are associated with gene sets with significant overlap and that are enriched in developmental processes.

This Article

  1. Published in Advance December 19, 2017, doi: 10.1101/gr.225896.117 Genome Res. 28: 145-158

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