Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

End of extended silent domains is defined locally and independently of transcriptional activity. (A) Sir3 binding at native and truncated TELVIIL, x-coordinates correspond with the native telomere TELVIIL. (B) Sir3 binding at TELVL in WT and Sir3-overexpressing (pGPD-SIR3) strains. Transcription factor (TF) binding and DNase I hypersensitive sites along TELVL are shown.

This Article

  1. Published in Advance October 24, 2018, doi: 10.1101/gr.236554.118 Genome Res. 28: 1867-1881

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research