Evolutionary conservation of Y Chromosome ampliconic gene families despite extensive structural variation

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Figure 1.
Figure 1.

Domestic cat Y Chromosome sequence content. (A) Ideogram of the domestic cat Y Chromosome. The purple and beige regions of the short arm represent the single and multicopy region of the Y Chromosome sequenced by Li et al. (2013). In the long arm, the colored blocks indicate the distribution of known ampliconic genes based on FISH analyses, with the corresponding genes being indicated in C. It is important to note that the resolution of the FISH analysis did not allow us to determine the extent to which the ampliconic region extends across the centromere. (B) Annotation of the Y Chromosome region as presented in Li et al. (2013). (C) Sequence content of 21 assembled BAC clones annotated with both transcripts (black arrows, text) and sequence origin (colors). Clones are placed in order by sequence content similarity, and this order is not reflective of their chromosomal position. (D) Annotated view of autosomal progenitor sequences with the representative color for each transposed region displayed below. Annotated loci are depicted in blue, and in silico–predicted loci are shown in orange. (E) Timeline of notable events in felid Y Chromosome evolution.

This Article

  1. Genome Res. 28: 1841-1851

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