The gene repressor complex NuRD interacts with the histone variant H3.3 at promoters of active genes

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Figure 4.
Figure 4.

H3.3 and NuRD co-occupy promoters of actively transcribed genes. (A) Correlation plots illustrating the relationship between enrichment of RBBP4, MTA1, and levels of various histone marks enriched ±1 kbp of TSSs. (B) Genes were categorized based on their expression level from low to high using RNA-seq data. Median promoter enrichment of NuRD subunits was plotted for each category. (C) Box plots showing median expression levels for genes that are bound by H3.3, H3.3 and NuRD, and NuRD alone.

This Article

  1. Genome Res. 28: 1646-1655

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