Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

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Figure 3.
Figure 3.

The pigmentation trait-associated variant, rs12203592, in IRF4 is a trans-eQTL for four genes in melanocytes. Cis- or trans-eQTL P-values and effect sizes (β) are shown between rs12203592 and IRF4 or rs12203592 and four genome-wide significant trans-eQTL genes (TMEM140, MIR3681HG, PLA1A, and NEO1). β values are shown relative to alternative alleles (T). Boxplots display gene expression levels based on rs12203592 genotypes (CC, CT, and TT).

This Article

  1. Published in Advance October 17, 2018, doi: 10.1101/gr.233304.117 Genome Res. 28: 1621-1635

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