Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome

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Figure 5.
Figure 5.

Comparative genomics of Lactobacillus spp. and estimated replication rates. (A) Multiple genome alignment of five L. iners genomes recovered through metagenomics along with the reference strain DSM 13335 (see Methods). A modified alignment created in Mauve shows the shared genomic context, as well as genomic islands unique to a strain (white areas within a conserved block). (B,C) Relative abundance and estimated genome replication values (iRep) for L. iners and L. crispatus, respectively.

This Article

  1. Genome Res. 28: 1467-1480

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