The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting

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Figure 3.
Figure 3.

Editing level profiles across different species. (AC) Heatmap of editing levels in human (A), mouse (B), and D.mel (C). For each species, only sites with editing levels ≥10% in at least one sample were selected for analysis. Human: (ACG) anterior cingulate gyrus. Tissues (bone marrow and liver) that have more than 50 missing editing values were removed from analysis. (D.mel: em) embryo; (L) larvae; (WPP) White prepupae; (AdF_Ecl) adult female eclosion; (AdM_Ecl) adult male eclosion. Samples (L1, L3 PS3-6, and WPP4) that have more than 50 missing editing values were removed from analysis. (DF), Pearson correlations for the editing levels of all sites in human (D), mouse (E), and D.mel (F). Gray means not available.

This Article

  1. Genome Res. 28: 132-143

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