The discrete expression modules of lncRNA expression by the WGCNA analysis. (A) Hierarchical clustering heat map of all differentially expressed lncRNAs (Fig. 2C, right) by samples. LncRNA modules were arranged from 0 (top) to 18 (bottom). (B) Hierarchical cluster dendrogram of all differentially expressed lncRNAs modules. Modules corresponding to branches are labeled with colors indicated by the color bands underneath the tree. (C) Eigengene bar plot of spatiotemporal modules of lncRNAs. Samples were first sorted by brain regions in the order of CB, DG, CA1, OC, TC, PC, PCC, and PFC. In each brain region, samples were then sorted by age (1 yr to 20 yr), and by sex (female and male). (D) Eigengene bar plot of tempo-spatial modules of lncRNAs in the same sample order as in C. (E1–E4) Eigengene bar plot of sex-temporal modules of lncRNAs in the same sample order as in C.
