Effects of background selection. (A) Comparison of the length of ELS regions in simulations of different scenarios. For the distribution under background selection, the s parameter corresponds to the average selection coefficient from the gamma distribution (shape parameter of 0.2). We assumed that the deleterious mutations are recessive with dominance coefficient h = 0.1. The horizontal blue line corresponds to the length cutoff applied to the real data. (B) Distribution of B-scores in the candidate sweep regions (red curve) compared to sets of random regions with matching physical lengths (blue area with dotted blue lines indicating the 95% confidence intervals over 1000 random sets of regions). The lowest B-score (i.e., stronger background selection) was chosen when a region overlapped several B-score annotations.
