Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes

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Figure 5.
Figure 5.

Functional analysis of rapidly evolving and highly sex-biased genes from the carcass of An. gambiae. (A) Relative proportions of putative functions among rapidly evolving sex-biased genes (sex-specific and strongly biased) in the carcass of An. gambiae. (B) Sex-biased expression ratios (in log2 fold change male/female) over sequence divergence rates (in dN/dS) for genes displaying strong bias or sex-specific expression in the carcass of An. gambiae. Horizontal box plots indicate dN/dS values for female- (red) and male-biased (blue) genes, highlighting the median values of each sex, which were used as a cutoff for downstream analysis. Genes with dN/dS value greater than the median of each sex are highlighted with putative functions using Gene Ontology (GO), orthology-based predictions, and community annotations (colored circles). Empty circles indicate genes evolving below our threshold of sequence divergence.

This Article

  1. Genome Res. 27: 1536-1548

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