Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

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Figure 4.
Figure 4.

Human–yeast genetic interaction network. Human orthologs of yeast genes whose deletion suppressed the toxicity of the 20 OMIM ORFs were identified. A network view of these human orthologs was generated using Cytoscape. The node color corresponds to the biological function category to which the gene belongs. The color of an edge indicates the type of interaction.

This Article

  1. Published in Advance June 8, 2017, doi: 10.1101/gr.211649.116 Genome Res. 27: 1487-1500

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