Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors

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Figure 5.
Figure 5.

(A) Somatic mutation spectra and transcriptional-strand bias for initial study of aflatoxin signatures in example human HCCs with likely aflatoxin exposure. Transcribed strand (Tr); nontranscribed strand (NT). Principal component analysis of (B) G > T and (C) G > N mutations for AFB1 experimental data (enclosed in irregular ovals) and HCCs with likely high aflatoxin exposure.

This Article

  1. Genome Res. 27: 1475-1486

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