Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of ST131

Comparison of antibiotic resistance of ST131, ST73, and the whole collection. Phenotypic antibiotic-resistance data are represented by the percentage of nonsusceptible (resistant + intermediate) isolates per year. Each subfigure represents one antibiotic class. Carbapenems (imipemen, meropenem, and ertapenem) and tigecycline are not shown due to the lack of resistance against these classes in this collection. (AMK) Amikacin; (GEN) gentamicin; (TOB) tobramycin; (TMP) trimethoprim; (CEF) cefalotin; (FOX) cefoxitin; (CXM) cefuroxime; (FEP) cefepime; (CTX) cefotaxime; (CAZ) ceftazidime; (AMX) amoxicillin; (AMP) ampicillin; (CIP) ciprofloxacin; (ATM) aztreonam; (AMC) amoxicillin-clavulanic acid; (TZP) piperacillin-tazobactam.