Single-cell sequencing deciphers a convergent evolution of copy number alterations from primary to circulating tumor cells

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Figure 5.
Figure 5.

CNAs in CTCs from individual patients and from different patients with the same type of cancer. (A) CNAs in five CTCs from a gastric cancer patient. (B) CNAs in CTCs from different gastric patients (one CTC was used for each patient). (C) CNAs in 15 CTCs from a breast cancer patient. (D) CNAs in CTCs from different breast cancer patients (one CTC was used for each patient). The bin size is 500 kb. The ordinate coordinate represents copy numbers ranging from 0 to 6 (a copy number of >6 copies is set to 6).

This Article

  1. Published in Advance May 9, 2017, doi: 10.1101/gr.216788.116 Genome Res. 27: 1312-1322

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