Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4.
Figure 4.

Early APC progenitor cells detected in CRC1. Raw sequencing reads and variant alleles are plotted for three diploid APC progenitor cells (PD16, PD41, PDD93) and one representative primary tumor cell (PA74) from the major tumor population at genomic regions where mutations were detected in APC, KRAS, TP53, and TCF7L2. Plots and read counts were generated using the Integrative Genomics Viewer (IGV).

This Article

  1. Published in Advance May 25, 2017, doi: 10.1101/gr.209973.116 Genome Res. 27: 1287-1299

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research